Washington [US], August 15 (ANI): Recent studies show that body weight fluctuations (or fluctuations in the classification of obesity index) increase the risk of cardiovascular-related problems and premature death in adults with chronic kidney disease (CKD). It is associated.
The survey results are published in the journal “JASN”.
Fluctuations in body mass index are associated with an increased risk of developing heart disease in the general population.
Because cardiovascular disease is the leading cause of death in CKD patients, a team led by Dong Ki Kim, MD, PhD, Sehoon Park, MD, and Kyungdo Han, PhD found that BMI fluctuations affect the prognosis of patients with renal dysfunction. I checked whether to give it.
The study included 84,636 CKD patients enrolled in the Korean National Health Examination Database. With a median follow-up of 4 years, 6% of individuals died, 4% required renal replacement therapy such as dialysis, 2% had a heart attack, and 3% had a stroke.
Individuals with the highest body mass index volatility are 66% more likely to die, 20% more likely to require renal replacement therapy, and have a heart attack and stroke compared to individuals with the lowest body mass index volatility. The risk of experiencing it is 19% higher.
“This study showed that people with renal dysfunction with recent changes in the classification of obesity index are at increased risk of cardiovascular disease or death, regardless of the current classification of obesity index,” said Seoul National University. Dr. Kim of the hospital said.
“This result shows that people with renal dysfunction should pay attention to weight fluctuations, and those with weight fluctuations should be properly screened and risk factors to prevent the progression of cardiovascular disease and renal dysfunction. It suggests that you may benefit from being managed, “added Dr. Kim.
The results were similar in the subgroups divided according to the positive / negative trends of BMI during the exposure assessment period.
In addition, changes in the components of certain metabolic syndromes were also significantly associated with the prognosis of predialysis patients with CKD.
In addition, those with a large number of components of the highly variable metabolic syndrome had a poor prognosis.
Co-authors of the study include Semin Cho, MD, Soojin Lee, MD, Yaerim Kim, MD, PhD, Sanghyun Park, Yong Chul Kim, MD, PhD, Seung Seok Han, MD, PhD, Hajeong Lee, MD, PhD, Includes JungPyo. Lee, MD, PhD, Kwon Wook Joo, MD, PhD, Chun Soo Lim, MD, PhD, and Yon Su Kim, MD, PhD. (ANI)
Weight fluctuations can increase adult health risk
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